02.07.2025 – Tirzepatide (Mounjaro) Medicine Interactions

Posted by: adambolton - Posted on:

Non-urgent advice: If you are taking Tirzepatide (Mounjaro) and oral contraceptive pills 

If you are taking or planning to take Tirzepatide (Mounjaro) this may mean that your contraception pills do not work effectively. If you are using the contraceptive pill, please use condoms for four weeks after each dose change, to avoid an unwanted pregnancy. This does not apply to semaglutide (Ozempic). Please contact the practice if you want to discuss your contraception.

Non-urgent advice: If you are taking weight loss injections (GLP-1 agonists such as Mounjaro) and oral progesterone as part of your HRT

If you are taking or planning to take weight loss injections and you take oral progesterone as part of your HRT (this includes Utrogestan (micronised progesterone), Medroxyprogesterone or if you take oral combined HRT e.g. Femoston, Elleste) please be aware that these medications can have an impact on the effectiveness of your HRT to adequately protect your endometrium (womb lining). Please contact the practice for a review so that your HRT can be appropriately adjusted.